过去一年中添加的文章,按日期排序
Characterisation of ligand gating, ion conduction and the ion selectivity mechanism in the endo-lysosomal ion channel hTPC2
AT Sahin, U Zachariae - bioRxiv, 2023 - biorxiv.org
42 天前 - … For this reason, TPCs represent prime targets for antiviral … a major target for the
development of antiviral drugs and … , voltage-gated ion channel superfamily, sharing sequence …
development of antiviral drugs and … , voltage-gated ion channel superfamily, sharing sequence …
Anti-Inflammatory and Analgesic Effects and Potential Targets of Shenzhu Jiedu Granule Against Novel Coronavirus Pneumonia Based on Network Pharmacology.
Y Zhang, WS Qi - Alternative Therapies in Health and Medicine, 2023 - europepmc.org
49 天前 - … Analysis revealed 72 key target proteins associated with the effects of Shenzhu
Jiedu … regulation, inflammatory cytokines, and ion channels in the microenvironment; KEGG …
Jiedu … regulation, inflammatory cytokines, and ion channels in the microenvironment; KEGG …
Nonspecific membrane bilayer perturbations by ivermectin underlie SARS-CoV-2 in vitro activity
RT Eastman, R Rusinova, KF Herold, XP Huang… - bioRxiv, 2023 - biorxiv.org
52 天前 - … μM) demonstrated that IVM could disrupt its purported antiviral target, the host
importin α/β1 … membrane-based targets such as GPCRs and noncanonical ion channels at low …
importin α/β1 … membrane-based targets such as GPCRs and noncanonical ion channels at low …
In Situ Spectroscopic Detection of Large‐Scale Reorientations of Transmembrane Helices During Influenza A M2 Channel Opening
RR Paschke, S Mohr, S Lange… - Angewandte Chemie …, 2023 - Wiley Online Library
84 天前 - … ion channels in membranes of enveloped viruses that play key roles during viral life
cycles. To use viroporins as drug targets … viroporins present a promising target for antiviral …
cycles. To use viroporins as drug targets … viroporins present a promising target for antiviral …
Fifty Years of Animal Toxin Research at the Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry RAS
V Tsetlin, I Shelukhina, S Kozlov… - International Journal of …, 2023 - mdpi.com
97 天前 - … with GABA-A receptors, and the strong antiviral effects of dimeric phospholipases
A2. A … ion channels. Apart from neurotoxins, diverse toxins acting on various biological targets …
A2. A … ion channels. Apart from neurotoxins, diverse toxins acting on various biological targets …
Antiviral Compounds to Address Influenza Pandemics: An Update from 2016-2022.
R Romeo, L Legnani, MA Chiacchio… - Current Medicinal …, 2023 - europepmc.org
99 天前 - … drugs able to interact with the different molecular targets involved in the virus …
able to target neuraminidase enzyme, hemagglutinin protein, Matrix-2 (M2) protein ion channel, …
able to target neuraminidase enzyme, hemagglutinin protein, Matrix-2 (M2) protein ion channel, …
Arbidol: The current demand, strategies, and antiviral mechanisms
Y Kang, Y Shi, S Xu - Immunity, Inflammation and Disease, 2023 - Wiley Online Library
109 天前 - … channel blockers, including amantadine and rimantadine, are common antiviral drugs
that can inhibit the M2 ion channel … Therefore, it can serve as the target of antiviral strategy…
that can inhibit the M2 ion channel … Therefore, it can serve as the target of antiviral strategy…
Rapid Determination of the Topology of Oligomeric α-Helical Membrane Proteins by Water-and Lipid-Edited Methyl NMR
114 天前 - … Single-span oligomeric α-helical transmembrane proteins are common in virus
ion channels, which are targets of antiviral drugs. Knowledge about the high-resolution …
ion channels, which are targets of antiviral drugs. Knowledge about the high-resolution …
Virtual screening and molecular growth guide the design of inhibitors for the influenza virus drug-resistant mutant M2-V27A/S31N
C Deng, X Wang, T Wang, W Liu, X Yuan… - Journal of …, 2023 - Taylor & Francis
165 天前 - … ) protein is a proton-gated, proton-selective ion channel essential for influenza
replication that has been identified as an antiviral target. The drug-resistance of the M2-V27A/…
replication that has been identified as an antiviral target. The drug-resistance of the M2-V27A/…
In-situ spectroscopic detection of large-scale reorientations of transmembrane α-helices during viroporin channel opening
RR Paschke, S Mohr, S Lange, A Lange, J Kozuch - bioRxiv, 2023 - biorxiv.org
175 天前 - … ion channels in membranes of enveloped viruses that play key roles during viral life
cycles. To use viroporins as drug targets … present a promising target for antiviral therapy. As …
cycles. To use viroporins as drug targets … present a promising target for antiviral therapy. As …